Categoria: Bibliografia Selezionata

Bavesh D Kana et al. Opportunities and challenges of leveraging COVID-19 vaccine innovation and technologies for developing sustnable vaccine manufacturing capabilities in Africa The Lancet, June 2023; doi.org/10.1016/S1473-3099(22)00878-7 Abstract The COVID-19 pandemic heralded unprecedented resource mobilisation and global scientific collaboration to rapidly develop effective vaccines. Regrettably, vaccine distribution has been inequitable, particularly in Africa where…

Huihui Wang et al. Modelling the economic burden of SARS-CoV-2 infection in health care workers in four countries Nature, May 2023; doi.org/10.1038/s41467-023-38477-7 Abstract Health care workers (HCWs) experienced greater risk of SARS-CoV-2 infection during the COVID-19 pandemic. This study applies a cost-of-illness (COI) approach to model the economic burden associated with SARS-CoV-2 infections among HCWs…

Hadeel T. Zedan et al. Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination JAMA, June 2023; doi:10.1001/jamanetworkopen.2023.19222 Abstract Importance  In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East respiratory syndrome coronavirus…

Peifang Sun et al. Antibody Responses to the SARS-CoV-2 Ancestral Strain and Omicron Variants in Moderna mRNA-1273 Vaccinated Active-Duty US Navy Sailors and Marines Academic.oup ; March 2023; doi.org/10.1093/infdis/jiad054 Abstract Omicron and its subvariants have steadily gained greater capability of immune escape compared to other variants of concern, resulting in an increased incidence of reinfections even…

Richard M Carpiano et al. Confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era The Lancet, march 2023; doi.org/10.1016/S0140-6736(23)00136-8 Abstract Over the past two decades, anti-vaccine activism in the USA has evolved from a fringe subculture into an increasingly well organised, networked movement with important repercussions for public health.…

Ruth E. Costello et al. Ethnic differences in the indirect effects of the COVID-19 pandemic on clinical monitoring and hospitalisations for non-COVID conditions in England: a population-based, observational cohort study using the OpenSAFELY platform The Lancet, June 2023; doi.org/10.1016/j.eclinm.2023.102077 Abstract The COVID-19 pandemic disrupted healthcare and may have impacted ethnic inequalities in healthcare. We aimed…

Nahla A. Alshaikh COVID-19 associated coagulopathy: A bibliometric investigation Cell, May 2023; doi.org/10.1016/j.heliyon.2023.e16507 Abstract Infection with SARS-CoV-2 initiates an immune-hemostatic response. While both systems are intimately connected and necessary for an efficient immune response to contain the infection, excessive coagulation activation might exceed the valuable benefits by causing thrombotic consequences and excessive inflammation. This biological…

ETIOLOGY – PATHOGENESIS – IMMUNOLOGY Adamo S, et al. Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection Nature, https://www.nature.com/articles/s41586-021-04280-x   Nabel KG, et al. Structural basis for continued antibody evasio n by the SARS-CoV-2 receptor binding domain Science, https://www.science.org/doi/10.1126/science.abl6251   Li X, et al. SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading…

Amin Addetia et al. Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail Cell, May 2023; doi.org/10.1016/j.celrep.2023.112621 Abstract Continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is eroding antibody responses elicited by prior vaccination and infection. The SARS-CoV-2 receptor-binding domain (RBD) E406W mutation abrogates neutralization mediated by the…

Michael Jäger et al. Immunity of Heterologously and Homologously Boosted or Convalescent Individuals Against Omicron BA.1, BA.2, and BA.4/5 Variants Academic.oup ;July 2023 ; doi.org/10.1093/infdis/jiad057 Abstract The emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants BA.1, BA.2, and BA.4/5 demonstrate higher transmission and infection rates than previous variants of concern. To evaluate effectiveness of heterologous…